attenuate or reduce in vigor, strength, or validity by polishing or purifying(verb.change)
Example: Many valuable nutrients are refined out of the foods in our modern diet.
source: wordnet30
make more precise or increase the discriminatory powers of(verb.change)
Example: Refine a method of analysis.
Refine the constant in the equation.
source: wordnet30
To reduce to a fine, unmixed, or pure state; to free from impurities; to free from dross or alloy; to separate from extraneous matter; to purify; to defecate; as, to refine gold or silver; to refine iron; to refine wine or sugar.(verb)
source: webster1913
To become pure; to be cleared of feculent matter.(verb)